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Materials Engineering & Material-Tissue Interactions

Division C - Department of Engineering

Studying at Cambridge


Brain Cancer Cell Mechanobiology

Glioblastoma multiforme (GBM) is the most common primary brain tumour, its most malignant form. GBM exhibits an extensive, rapid and infiltrative growth pattern. Prognoses and patient quality of life are poor, due in part to the non-specific and toxic nature of conventional treatment options (chemotherapy and radiation therapy), hence there is a pressing need for new and more targeted therapeutic options. The group aims to test the efficacy of novel immuno-therapeutic treatments. Understanding GBM cell migration and the factors that affect cell adhesion are important for the development of novel therapeutic strategies. The project is carried out in collaboration with Dr Colin Watts (Department of Clinical Neurosciences, Division of Neurosurgery, Addenbrooke's Hospital).


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